Experimental & molecular medicine
Microglial CX3CR1 deficiency regulates the selective vulnerability of cone photoreceptors via STAT3/CCL-ACKR1 signaling in the mouse retina.
Rong Li, Jing Zhang, Qiong Wang, Jun-Qi Fan, Bin Lin
Published: 202610.1038/s12276-025-01618-7
Abstract
Selective neuronal vulnerability is a common feature of neurodegenerative disorders. However, the molecular mechanisms that drive this selective vulnerability are not fully understood. Here we observed that microglial CX3CR1 interference induced proi…
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