Journal of the American Society for Mass SpectrometryOligonucleotidesTandem Mass SpectrometryProtonsModelsChemical
Prediction of Collision-Induced Dissociation Spectra of Deprotonated Oligonucleotides.
Zhongqi Zhang, Jason Richardson
Published: 202510.1021/jasms.5c00295
Abstract
Developing DNA/RNA-based therapeutics (siRNA, antisense oligonucleotides, mRNA, etc.) requires comprehensive tools for structural characterization. MS/MS remains a main tool for structural characterization of short synthetic DNA/RNA or oligonucleotid…
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