Journal of the American Society for Mass SpectrometryTandem Mass SpectrometryHumansImmunoglobulin Light ChainsMultiple MyelomaFourier Analysis
Top-Down Mass Spectrometry of a Clinical Antibody Light Chain Using the Omnitrap-Orbitrap-Booster Platform.
Camille Garcia, Nina A Khristenko, TingTing Fu, Karen Druart, Konstantin O Nagornov, Marie Yammine, Athanasios Smyrnakis, Anton N Kozhinov, Dimitrios Papanastasiou, Yury O Tsybin, Julia Chamot-Rooke
Published: 202510.1021/jasms.5c00256
Abstract
The Omnitrap-Orbitrap-Booster (OOB) mass spectrometry (MS) platform was developed to advance the top-down (TD) MS analysis of proteins. It integrates a multimodal tandem mass spectrometry (MS/MS) ion trap system (Omnitrap), a high-resolution Orbitrap…
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