Journal of the American Chemical Society
Pd(II)-Catalyzed Asymmetric [4 + 1] Annulation via Ligand Relay-Enabled Carbenylative Insertion/E1cB-Type Heck Cascade.
Zhou Luo, Yi-Hao Zhang, Chao Zhang, Kewei Dong, Pranab K Pramanick, Shen Zhao, Yuanyuan Liu, Guoqiang Yang
Published: 202610.1021/jacs.5c20265
Abstract
Pd-catalyzed asymmetric annulation via metal carbene is highly desired for efficient access to chiral cyclic compounds; however, such a strategy remains a considerable challenge. In this study, we report an unprecedented Pd-catalyzed asymmetric [4 +…
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