Journal of the American Chemical SocietyKetoglutaric AcidsAnimalsMiceAlzheimer DiseaseHumans
Chiral Spindle-like Nanorods Reprogram Neuroinflammation by Catalyzing α-Ketoglutarate Biosynthesis.
Jingqi Dong, Liguang Xu, Xinxin Xu, Baimei Shi, Qing Wang, Jun Xu, Chuanlai Xu, Hua Kuang, Aihua Qu
Published: 202610.1021/jacs.5c19753
Abstract
Alzheimer's disease (AD) is the most prevalent cause of dementia worldwide, and breakthroughs in effective intervention strategies are urgently needed. Here, we report that chiral spindle-like Fe7Se8 nanorods (NRs) promote α-ketoglutarate (AKG) biosy…
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