Journal of the American Chemical Society
Chemical Synthesis of Native ADP-Ribosylated Oligonucleotides Enables Analysis of DNA ADP-Ribosylation Hydrolase Specificity.
Li Tang, Yang Lu, Femke L A M van der Heijden, Yanrong Chen, Shuyan Jiang, Nico J Meeuwenoord, Lingxiao Liu, Zongxing Yu, Zhenrong Chen, Marion Schuller, Dmitri V Filippov, Ivan Ahel, Qiang Liu
Published: 202610.1021/jacs.5c17532
Abstract
ADP-ribosylation (ADPr) is a modification by which an ADP-ribose moiety is conjugated to different molecules by ADP-ribosyltransferases (ARTs) to control various cellular processes in organisms from all kingdoms of life. While traditionally considere…
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