Journal of the American Chemical SocietyHydrogenaseRubredoxinsNickelNuclear Magnetic ResonanceBiomolecular
Correlating Protein Dynamics and Catalytic Activity of a Model Hydrogenase Using Paramagnetic and Biological Nuclear Magnetic Resonance Spectroscopy.
Pathorn H Teptarakulkarn, Regina E Treviño, Alexandar L Hansen, Joseph A Laureanti, Garry W Buchko, Wendy J Shaw, Hannah S Shafaat
Published: 202610.1021/jacs.5c15958
Abstract
Rational catalyst design remains a significant challenge, with electronic structure, steric, and electrostatic effects known to contribute to activity. Recently, dynamics has been recognized as another factor that impacts catalysis, though identifyin…
Preview only. Read the full abstract at the source