Journal of the American Chemical SocietyPhotosensitizing AgentsAnimalsMiceMacrophagesHumans
Responsive Photosensitizer Precursors Reverse Drug-Induced Secondary Immunosuppression.
Shan Zuo, Huiyi Liu, Gangwei Jiang, Yushi Chen, Tianbing Ren, Zhixuan Zhou, Xiao-Bing Zhang, Lin Yuan
Published: 202510.1021/jacs.5c15227
Abstract
Pharmacological treatments, common methods for inhibiting tumor cell proliferation, often concurrently induce secondary immunosuppression. Reprogramming tumor-associated macrophages (TAMs) from an M2 to M1 phenotype via photosensitization offers a pr…
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