Journal of the American Chemical Society
Annulative Skeletal Diversification of Pyrimidines to Expanded Heteroaromatic Space.
Philipp Spieß, Atang S Peloewetse, Antonia Profyllidou, Samantha L Kraus, Nicolò Santarelli, Takashi Fukuyama, Jeffrey T Kohrt, Caroline A Blakemore, Christina G Na, Richmond Sarpong, Scott W Bagley
Published: 202510.1021/jacs.5c14511
Abstract
Single-atom skeletal editing has recently emerged as a powerful strategy for the direct diversification of the heterocyclic cores of various compounds. Yet, methods that enable monocycle-to-bicycle transformations that involve core atom changes remai…
Preview only. Read the full abstract at the source