Journal of the American Chemical Society
Hydrogen Isotope Exchange of Aromatic C(sp2)-H Bonds via Electron Donor-Acceptor Organic Photocatalysis.
Riley Y Way, Xuewen Guo, Yao Tang, Josephine B Shirah, Qilei Zhu
Published: 202510.1021/jacs.5c14203
Abstract
Despite the recent emergence of photocatalytic strategies for incorporating heavier hydrogen isotopes─deuterium and tritium─in therapeutic molecules, most established methods focus on the cleavage and labeling of relatively weak C(sp3)-H bonds adjace…
Preview only. Read the full abstract at the source