Journal of the American Chemical SocietyNuclear Magnetic ResonanceBiomolecularAzo CompoundsLightProteins
Light-Driven Paramagnetic Tags for Efficient Pseudocontact Shifts Measurements in Protein NMR Spectroscopy.
Zhaofei Chai, Qiong Wu, Kai Cheng, Weixuan Wang, Jiawen Chen, Xiaoli Liu, Yujun Xie, Zhen Li, Ling Jiang, Conggang Li
Published: 202510.1021/jacs.5c13482
Abstract
Pseudocontact shifts (PCSs) are essential for studies of protein structures and dynamics. However, structural calculations typically require multiple tags or labeling at multiple sites, which can be both time-consuming and expensive. In this study, w…
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