Journal of the American Chemical SocietyCyclopropanesStereoisomerismAldehyde-LyasesBiocatalysisMolecular Structure
Stereoselective De Novo Construction of Cyclopropane by a Multifunctional Class I Aldolase.
Yulian Li, Qiaoqiao Li, Rui Zhang, Cangsong Liao
Published: 202510.1021/jacs.5c13402
Abstract
Cyclopropane is a widely distributed structural unit in natural products and pharmaceuticals. Current strategies in both organic and enzymatic synthesis of cyclopropane scaffolds mainly rely on alkene-based transformations, and de novo construction o…
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