Journal of the American Chemical SocietyBiological ProductsAmidesMultigene FamilyLigasesPeptides
Deazapurine Amide-Bond Synthetases: a New Family of Amide-Bond-Forming Enzymes Driving the Diversity of Peptidyl Deazapurine Natural Products.
Chang-Hun Ji, Chan-Ik Kim, Boin Yun, Jun-Yong Kim, Sangwook Kang, Dong-Chan Oh, Hahk-Soo Kang
Published: 202510.1021/jacs.5c13285
Abstract
Amide bond-forming enzymes play a crucial role in generating structural diversity in natural products by assembling them from relatively simple precursors. Two distinct types of standalone amid-bond-forming enzymes are commonly involved in natural pr…
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