Journal of the American Chemical SocietyGlioblastomaAnimalsMiceNanoparticlesHumans
Genetically Engineered Biomimetic Nanoparticles for Synergistic Activation of Glioma-Associated Macrophages against Glioblastoma.
Jia-Qi Luo, Ji Zhang, Hui-Han Yu, Yu-Xuan Li, Zhong-Hong Zhou, Yuyou Duan, Jin-Zhi Du, Jun Wang
Published: 202510.1021/jacs.5c12775
Abstract
Glioma-associated macrophages (GAMs) are central mediators of immune evasion and therapeutic resistance in glioblastoma multiforme (GBM) due to their tumor-promoting M2 phenotype and loss of phagocytic activity toward tumor cells. Activating GAMs rep…
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