Journal of the American Chemical SocietyAntioxidantsAcute Kidney InjuryAnimalsCopperStereoisomerism
Chirality-Driven Metal-Phenolic Artificial Enzymes Enable Renal Targeting and Antioxidative Therapy Enhancement for Acute Kidney Injury.
Zhiwei Wei, Liya Wang, Li Yang, Shengqiu Chen, Yiming Chen, Zhibin Lu, Ke Zhang, Baihai Su, Yi Xie, Changsheng Zhao
Published: 202510.1021/jacs.5c12337
Abstract
Despite advancements in artificial enzymes (AEs) for acute kidney injury (AKI) therapy through renal redox homeostasis modulation, the trade-off between organ-specific targeting and high multienzyme-mimicking catalytic efficiency is still a big chall…
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