ACS synthetic biology
PTET-DDI: Dual-Channel Drug-Drug Interaction Prediction with a Pre-Trained Language Model and Equivariant Graph Transformer.
Xiaofeng Man, Chao Sun, Zhuo Chen, Yuanyuan Ji, Junwei Du, Bin Yu
Published: 202610.1021/acssynbio.5c00722
Abstract
Combination therapy is widely used in clinical practice, rendering accurate prediction of drug-drug interactions (DDIs) essential for treatment safety and efficacy. This paper proposes PTET-DDI, a novel dual-channel framework that synergizes chemical…
Preview only. Read the full abstract at the source