ACS synthetic biologyAnimalsCHO CellsCricetulusAntibodiesMonoclonal
Microfluidic Chip-Based In Vitro Screening System of Synthetic Signal Peptides for Enhanced Monoclonal Antibody Production in Chinese Hamster Ovary Cells.
Na-Yeong Heo, So-Hui Ryu, Jong-Ho Park, Hyun-Seung Kim, Jungsoo Kim, Heungchae Jung, Jungmok You, Yeon-Gu Kim
Published: 202510.1021/acssynbio.5c00563
Abstract
Establishing an in vitro screening system for synthetic signal peptides in Chinese hamster ovary (CHO) cells is crucial, as selecting an appropriate signal peptide ensures efficient secretion and enhances therapeutic protein production. However, expa…
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