ACS synthetic biologyIntrinsically Disordered ProteinsNucleic Acid HybridizationMolecular ChaperonesKineticsDNA
Smart Nucleic Acid Chaperones: Phase-Separating Intrinsically Disordered Proteins for Accelerating DNA Hybridization Reactions.
Telmo Díez Pérez, Ashley N Tafoya, David S Peabody, Carina N Anastasio, Andrew P Shreve, Matthew R Lakin, Nick J Carroll, Gabriel P López
Published: 202610.1021/acssynbio.5c00511
Abstract
Nucleic acid (NA) hybridization reactions are central to molecular biology and NA nanotechnologies, which exploit base-pairing to generate intricate structures and dynamic reaction systems. NA chaperones are molecules (typically proteins) that can ca…
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