ACS sensorsCRISPR-Cas SystemsHumansOligonucleotidesAntisenseNucleic Acid Amplification Techniques
CRISPR/Cas12a with Antisense Oligonucleotide-Regulated Translational Amplification for Ultrasensitive Nucleic Acid Detection.
Yoo-Hong Min, Deok-Gyu Lee, Ha-Yeong Lee, Jin-Hee Yoo, Kyung-Ho Lee, Yong-Beom Shin, Ju-Young Byun
Published: 202610.1021/acssensors.5c03081
Abstract
Highly sensitive nucleic acid testing-assisted early disease detection is crucial for effective disease prevention and management, particularly when targeting low-abundance genetic materials in molecular diagnostics. This study describes CRATE (CRISP…
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