ACS nanoReactive Oxygen SpeciesAnimalsPlatinumFemaleMice
Bone-Targeted Platinum Nanoframework Prevents Postmenopausal Osteoporosis via Transmembrane Protein 16A Channel Blockade and Reactive Oxygen Species Scavenging.
Donghong Shi, Meng Tian, Yuling Li, Mengge Xue, Xiaoling Zhao, Jinping Wang, Hailong An
Published: 202610.1021/acsnano.5c19260
Abstract
Postmenopausal osteoporosis (POP) in women caused by estrogen deficiency leads to an increase in reactive oxygen species (ROS) within the osteoporotic microenvironment, thereby promoting osteoclastogenesis mediated by the receptor activator of the nu…
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