ACS nanoCell MovementMechanotransductionCellularHumansCell Nucleus
Curved Microfluidic Confinement Reveals Cell-Shape-Dependent Nuclear Mechanotransduction in Adaptive Migration.
Yu-Chen Chen, Yixin Liu, Sai-Xi Yu, Ya-Jun Wang, Wei Liu, Yuxian Liao, Xue-Zhu Chen, Hai Gao, Baohong Liu, Yan-Jun Liu
Published: 202610.1021/acsnano.5c16455
Abstract
Cells navigate within diverse curved microenvironments derived from extracellular matrix (ECM) and neighboring cells in vivo. While current studies primarily focus on cell migration on curved surfaces, cellular adaptive responses to confinement-coupl…
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