ACS nanoCholesterolImmunotherapyCatalysisMiceAnimals
Piezoelectricity-Potentiated Bioorthogonal Catalysis Disrupts Cholesterol Metabolism for Tumor Immunotherapy.
Mengyu Sun, Qi Wang, Li Wu, Yanjie Zhang, Jinsong Ren, Xiaogang Qu
Published: 202510.1021/acsnano.5c14098
Abstract
Cholesterol metabolism plays a pivotal role in cancer progression and immune evasion. However, the adverse side effects of cholesterol-lowering medications, resulting from off-target activity and high-dose requirements, represent a serious bottleneck…
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