ACS nanoProtein StabilityMolecular Dynamics SimulationProtein BindingPolymersMethacrylates
Random Heteropolymers Enable Nonspecific Protein Binding and Loop-Mediated Stabilization.
Tianyi Jin, Akorfa Dagadu, Connor W Coley, Alfredo Alexander-Katz
Published: 202510.1021/acsnano.5c12927
Abstract
Membrane proteins play essential roles in cellular signaling, transport, and catalysis, but their structural instability outside of lipid bilayers presents a major challenge for biophysical studies and therapeutic applications. Here, we demonstrate t…
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