ACS nanoAnimalsImmunotherapyMyeloid CellsMiceNanoparticles
A Myeloid Cell-Targeted Immunostimulant Cocktail (MyTai) Enhances Cancer Immunotherapy.
Hyung Shik Kim, Grant G Simpson, Jasmine Carrothers, Yen T M Nguyen, Rainer Kohler, Seungbeom Hong, Seungbin Cha, Dong Ho Kim, Christopher S Garris, Ralph Weissleder
Published: 202510.1021/acsnano.5c10081
Abstract
The efficacy of tumor vaccines depends in large part on additional immunostimulation of antigen-presenting cells (APC) in tumor microenvironments. Various Toll-like receptors (TLR), and in particular TLR3 stimulation by dsRNA, generate a cellular imm…
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