ACS nanoAnimalsReceptorsChimeric AntigenMiceRNA
In Situ Chimeric Antigen Receptor Macrophage Therapy via Co-Delivery of mRNA and Immunostimulant.
Jun-Hee Han, Erinn Fagan, Kyunghwan Yeom, Ji-Ho Park
Published: 202510.1021/acsnano.5c09138
Abstract
Cancer immunotherapy employing chimeric antigen receptor (CAR) technology has achieved significant clinical success in hematologic malignancies, but faces limitations in solid tumors. Among alternative strategies, CAR-macrophage therapy offers distin…
Preview only. Read the full abstract at the source