ACS infectious diseasesCapsid ProteinsHumansVirus AssemblyPolyelectrolytesHeparin
Polyanionic Sugars Drastically Affect Assembly of Human Papilloma Virus Virus-Like Particles.
Angela Patterson, Kim Young, MacRyan P Biever, Shelby M Klein, Stephen C Jacobson, Martin F Jarrold, Adam Zlotnick
Published: 202610.1021/acsinfecdis.5c00896
Abstract
The L1 capsid protein of Human papilloma virus 16 (HPV16) forms pentamers that assemble into virus-like particles (VLPs). With many viruses, interaction of the virus with polysaccharides modulates association of the virus with a host cell. For HPV16,…
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