ACS chemical neuroscienceAnimalsSpinal Cord InjuriesMiceRecovery of FunctionKnockout
Proton-Activated Chloride Channel Modulates Motor Function after Acute Spinal Cord Injury.
Jianwei Wu, Wenbiao Xiao, Zian Lu, Han Huang, Haocheng Xu, Zhenhao Chen, Hongli Wang, Jing Feng
Published: 202610.1021/acschemneuro.5c00855
Abstract
Spinal cord injury (SCI) disrupts motor, sensory, and autonomic functions, profoundly impairing quality of life. Here, we investigate the role of the proton-activated chloride (PAC) channel, encoded by Pacc1, in motor function recovery following SCI.…
Preview only. Read the full abstract at the source