ACS chemical neurosciencealpha-SynucleinNanoparticlesAnimalsCardiolipinsHumans
Cardiolipin-Based Nanoparticles Inhibit α-Synuclein Fibrilization.
Morgan G Stykel, Justin Medeiros, Tammy L Ryan, Shehani V Siripala, Suelen Carmago, Ping Lu, Vladimir V Bamm, Carla L Coackley, Scott D Ryan
Published: 202610.1021/acschemneuro.5c00688
Abstract
Synucleinopathies are a group of neurodegenerative disorders characterized by structural aberrations in the protein alpha-synuclein (α-syn). In these disorders, α-syn accumulates and misfolds, contributing to the formation of intracellular inclusion…
Preview only. Read the full abstract at the source