ACS chemical neuroscienceFluorescent DyesAmyloid beta-PeptidesAnimalsSolubilityBoron Compounds
Novel BODIPY-Based Fluorescent Probes with Improved Aqueous Solubility for Selective Detection of Soluble Aβ Aggregates.
Takahiro Akasaka, Hiroyuki Watanabe, Masahiro Ono
Published: 202510.1021/acschemneuro.5c00525
Abstract
Soluble amyloid β (Aβ) aggregates have attracted attention as therapeutic targets and biomarkers of Alzheimer's disease. We previously reported a fluorescent probe, BAOP-16, which targets soluble Aβ aggregates. However, its limited aqueous solubility…
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