ACS chemical biologyCitrullinationHumansProteomeProteomicsLysine
Development of a Chemoproteomic Platform to Identify Sites of (Homo)citrullination within Complex Proteomes.
Sarah A Mann, Leonard Barasa, Paul R Thompson, Eranthie Weerapana
Published: 202510.1021/acschembio.5c00694
Abstract
Citrullination and homocitrullination of arginine and lysine can significantly impact protein structure and function. Citrullination of arginine is an enzymatic modification catalyzed by Protein Arginine Deiminases (PADs). Homocitrullination of lysin…
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