ACS biomaterials science & engineering
Spatiotemporally Adaptive and Stage-Matched Tissue-Engineered Constructs for MRSA Osteomyelitis: Pathogenesis-Informed Design.
Rui Zhang, Yijing Stehle, Mao Yang, Ke Zeng, Mingyue Lin, Chenxin Wang, Huanshuo Zhang, Jiehui Yang, Denglang Hu, Min Huang, Yubao Li, Li Chen, Qin Zou
Published: 202610.1021/acsbiomaterials.5c02000
Abstract
Objective: Osteomyelitis, particularly caused by methicillin-resistant Staphylococcus aureus (MRSA), often leads to significant infected bone defects and poses substantial challenges for functional reconstruction. Conventional one-stage interventions…
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