ACS biomaterials science & engineeringCystic FibrosisBioreactorsAnimalsHumansGenetic Therapy
Airway-to-Go: An Ex Vivo Cystic Fibrosis Airway Model and Bioreactor System for High Throughput Gene Therapy Screening.
Maria R Hudock, Griffin W Daly, Daniel Rivas, Aneri Patel, Jiawen Chen, Margaretha A J Morsink, Ylleana S Goduco, Meghan R Pinezich, Mohammad Mir, Julie Van Hassel, Mohamed Diane, Alexander Yoon, Olimpia P Gavaudan, Tyrone Baines, Po-Jen Yun
Published: 202510.1021/acsbiomaterials.5c01527
Abstract
Despite three decades of progress since the cystic fibrosis transmembrane conductance regulator (CFTR) gene was discovered, there is still no gene therapeutic cure for the lethal pulmonary component of cystic fibrosis (CF). Existing CF models fall sh…
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