ACS biomaterials science & engineeringHydrogelsMesenchymal Stem CellsAnimalsMiceSpheroids
Modulating iMSC Spheroid Function with Mechanically Tunable Hydrogels to Strengthen the Bone-Muscle Axis.
Thi Thai Thanh Hoang, Andrea C Filler, David H Ramos-Rodriguez, Ki Dong Park, J Kent Leach
Published: 202610.1021/acsbiomaterials.5c01400
Abstract
Bone fractures often involve both bone and muscle damage, representing a critical need for regenerative strategies that can repair both tissues. We developed a gelatin-based hydrogel system with tunable stiffness to guide spheroids formed from induce…
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