ACS biomaterials science & engineeringTumor MicroenvironmentFemaleBreast NeoplasmsHumansAnimals
Activating Immunogenic Cell Death and Reprogramming the Tumor Microenvironment to Enhance Radiotherapy for Breast Cancer via Low-Frequency Ultrasound-Driven "Artificial T Cells".
Lei Dong, Ran Li, Hanjiao Liu, Jiangtao Yue, Zhengcheng Yun, Junfan Wei, Yinzhuo Xie
Published: 202510.1021/acsbiomaterials.5c01048
Abstract
The immunosuppressive tumor microenvironment (TME) is a key factor that reduces the effectiveness of radiotherapy in breast cancer, as it limits the ability of cytotoxic T lymphocytes (CTLs) to effectively target and eliminate tumor cells. In this st…
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