ACS applied materials & interfaces
Mechanical Memory Induction by Microgrooved Hydrogels Enables Stem Cell-Driven Cartilage Repair.
Siying Wu, Ying Wang, Haoran Feng, Ziyan Wang, Yang Liu, Yuanhao Fan, Yonghao Pan, Lulu Zhou, Qiuchi Xu, Jiawei Li, Assanali Sultanbekov, Jianqun Wu, Fangyi Chen, Yiming Li, Decheng Wu
Published: 202610.1021/acsami.5c20922
Abstract
Mechanical memory, or when cells retain traits from their physical environment, influences stem cell fate. During cartilage repair, the extra-cellular mechanical microenvironment could direct stem cell behavior through mechanical memory. In this stud…
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