ACS applied materials & interfacesDiphosphonatesContrast MediaGadoliniumMagnetic Resonance ImagingNanoparticles
Synthesis and Characterization of Bisphosphonate-Functionalized Gadolinium Oxide Nanoparticles as Nonionizing Contrast Agents to Detect Bone Turnover.
Adibehalsadat Ghazanfari, David J Pérez, Antonio Vega-Medina, Carlos A Velázquez-Martínez, Richard B Thompson, Jacob L Jaremko, Neal M Davies, Michael R Doschak
Published: 202510.1021/acsami.5c20797
Abstract
We developed a one-pot polyol synthetic strategy for generating bisphosphonate-conjugated citric acid gadolinium oxide nanoparticles (BP-GdOx-NPs) for use as a medical imaging contrast agent to detect bone turnover. This agent, akin to the current nu…
Preview only. Read the full abstract at the source