ACS applied materials & interfacesAnimalsReactive Oxygen SpeciesMitochondriaMacrophagesRats
Hierarchically Targeting and ROS-Responsive Platform for Diabetic Periodontitis Treatment through Mitochondrial Repair in M1 Macrophages.
Wenjia Xie, Yuxuan Wang, Jicenyuan Wu, Xu Wang, Jiaxin Wu, Bin Cheng, Hao Feng, Xinxu Huang, Xinting Cheng, Junyu Chen, Qianbing Wan, Jian Wang, Xibo Pei
Published: 202610.1021/acsami.5c20136
Abstract
Diabetic periodontitis is characterized by persistent and aggravated inflammation, largely driven by a reactive oxygen species (ROS) vicious loop in M1 macrophages driven by mitochondrial dysfunction. To disrupt this pathogenic cascade, we developed…
Preview only. Read the full abstract at the source