ACS applied materials & interfacesHumansPhotosensitizing AgentsPhotochemotherapyAnimalsMice
AIE-Active Photosensitizer APT NPs with Type I/II ROS Generating Orchestrate the DDIT4-Centric Gene-Metabolite Axis in Photodynamic Therapy.
Zhen Fang, Mei Li, Yali Mai, Wenlong Luo, Ergang Wang, Xinchun Liu, Chengyong Yang, Zhongqing Shen, Yanshan Liu
Published: 202510.1021/acsami.5c19205
Abstract
Photodynamic therapy (PDT) is a promising strategy for tumor treatment; however, the oxygen adaptation of conventional photosensitizers, coupled with the elusive mechanism, has greatly hindered their further development. Here, a novel organic aggrega…
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