ACS applied materials & interfacesCD47 AntigenAnimalsMacrophagesFemaleImmunotherapy
Manganese-Mediated CD47 Epitope-Imprinted Nanotraps for Stage-Adaptive Macrophage Reprogramming and Photothermal Immunotherapy of Breast Cancer.
Xian Li, Xiao Tian, Jiantao Chen, Mei Yao, Weige Dong, Ruifang Bai, Siyuan Qin, Yu Wan, Chungu Zhang, Ming-Yu Wu, Shun Feng
Published: 202510.1021/acsami.5c16275
Abstract
Current macrophage-centric immunotherapies face limitations in systemic toxicity, targeting precision, and stage-specific adaptability. To address these challenges, we engineer manganese-mediated CD47 epitope-imprinted nanotraps (Mn-MIP nanotraps) vi…
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