ACS applied materials & interfacesLab-On-A-Chip DevicesStressMechanicalExtracellular MatrixPressure
Tunable Stiffness of Matrix-Derived Membranes Enables Independent and Coupled Analysis of Pressure and Strain Effects in Barrier Tissue-On-Chip Models.
Jeremy D Newton, Samantha Hossain, Kimia Abedi, Yuetong Song, Jacqueline Pavelick, Claudia C Dos Santos, Amy Wong, Edmond W K Young
Published: 202510.1021/acsami.5c15966
Abstract
Organ-on-a-chip (OOC) devices modeling thin barrier tissues often incorporate features of the mechanical microenvironment which play regulatory roles in maintaining tissue function. In contexts where tissues are exposed to complex combinations of for…
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