ACS applied materials & interfacesAnimalsMetal-Organic FrameworksFemaleHumansMice
A Metal-Organic Framework Nanocarrier System for Precise Targeted Delivery and Reduced Systemic Toxicity of Mitoxantrone in Breast Cancer Therapy.
Xiaowen Xu, Youjia Wu, Lingyi Huang, Pingping Wu, Liying Huang
Published: 202510.1021/acsami.5c14630
Abstract
Mitoxantrone (MTX) is a first-line chemotherapeutic agent. However, it has some limitations, such as poor tumor targeting, systemic toxicity, etc. A precise delivery system for MTX was developed using β-Cyclodextrin-modified redox/pH dual-responsive…
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