ACS applied bio materials
Structural Dynamics of Peptiplexes Formed between Cationic Cell-Penetrating Peptides and DNA: A Comparative Study on TAT-HIV and NLS-SV40T.
Lucas R de Mello, Ibrahim A Siddiq, Bianca B M Garcia, Ian W Hamley, Karin A Riske, Sang W Han, Guillaume Tresset, Yves Lansac, Yun Hee Jang, Emerson R da Silva
Published: 202610.1021/acsabm.5c01567
Abstract
Biomembranes evolved to protect cells and regulate exchange, forming a powerful barrier to large, charged macromolecules such as nucleic acids. In recent years, this paradigm has been competently overturned by soft biomaterials based on cell-penetrat…
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