ACS applied bio materialsTriple Negative Breast NeoplasmsLiposomesSorafenibPolyethylene GlycolsAntineoplastic Agents
Lipid-Extruded PEGylated Liposomes of Repurposed Sorafenib for Triple-Negative Breast Cancer: A Mechanistically Enhanced Nanoplatform with Improved In Vivo Pharmacokinetics and Targeted Biodistribution.
Avinash Pawar, Ekta Pardhi, Neelesh Kumar Mehra
Published: 202510.1021/acsabm.5c01119
Abstract
Sorafenib Tosylate (SRT), a multikinase inhibitor originally approved for several solid tumors, has been repurposed for potential application in triple-negative breast cancer (TNBC) due to its multitargeted antitumor mechanisms. However, its clinical…
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