ACS applied bio materialsAscorbic AcidCeriumAntineoplastic AgentsAnimalsMice
Ascorbate-Triggered Antitumor Activity of Nanoceria- and Ceria-Based Supramolecular Complexes in 2D and 3D Cell Cultures.
Nataliya Kavok, Galyna Dudetskaya, Vladyslav Seminko, Pavel Maksimchuk, Yurii Kot, Olga Sedyh, Kateryna Hubenko, Olga Vashchenko, Vladimir Klochkov, Svetlana Yefimova
Published: 202510.1021/acsabm.5c00916
Abstract
Supramolecular complexes (SMCs) based on cholesterol, menadione, and redox-active ceria nanoparticles (NPs) with a pronounced antitumor effect triggered by the addition of ascorbic acid were obtained. Ascorbic acid plays the role of electron donor, i…
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