Organic letters
Solution-Phase and Mechanochemical Brønsted-Acid-Catalyzed N-Alkylation of NH-Heterocycles via Hydroamination of Vinyl Ethers.
Vikash Kumar, Rajaram Maayuri, L N S Laya Pagadala, Mahesh Kumar Ravva, Parthasarathy Gandeepan
Published: 202610.1021/acs.orglett.6c00125
Abstract
A Brønsted-acid-catalyzed hydroamination of vinyl ethers with carbazoles was developed using diphenyl hydrogen phosphate (DPHP) as the catalyst. The method enables the efficient, regioselective N-alkylation of various carbazoles and NH-heterocycles u…
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