Organic letters
Base-Mediated Cascade Annulations of β-CF3-1,3-Enynamides with Tosylaminomethyl Enones: Synthesis of Angularly CF3-Substituted Hexahydrocyclopenta[c]pyrrole Frameworks.
Tianyu Chen, Sunle Zhu, Jianrong Zhang, Shiqing He, Yuanjing Xiao
Published: 202610.1021/acs.orglett.5c05301
Abstract
A base-mediated cascade [3 + 2]/[2 + 3] annulation of β-CF3-1,3-enynamides with tosylaminomethyl enones affording highly functionalized angularly CF3-substituted hexahydrocyclopenta[c]pyrrole frameworks, which are challenging to prepare via conventio…
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