Organic letters
Photocatalytic Kharasch-Type Cyclization Cascade for Accessing Polyhalogenated 1-Indanones and Indenes.
Yan Zhang, Zi-Yang Xu, Rong Fu, Ke Chen, Wen-Juan Hao, Bo Jiang
Published: 202610.1021/acs.orglett.5c05236
Abstract
A new photocatalytic cascade involving Kharasch-type cyclization, 1,5-(SN″)-substitution, and elimination has been developed for the reactions of secondary alcohol-tethered 1,6-diynes with polyhalomethanes such as BrCCl3 and CBr4. This method affords…
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