Organic letters
Asymmetric Iodoaminocyclization for the Synthesis of Chiral 2-Heteroaryl Pyrrolidines.
Yangyang Zhong, Kehan Zhao, Kewen Zhong, Tianlan Zhao, Hongping Zhu, Huijing Wang, Fener Chen
Published: 202610.1021/acs.orglett.5c05072
Abstract
An asymmetric iodoaminocyclization strategy catalyzed by (DHQD)2PHAL has been developed for the synthesis of chiral 2-heteroaryl pyrrolidines, including 2-purinyl and 2-indolyl analogues. This method proceeds under mild conditions and affords the tar…
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