Organic letters
Oxidative Quenching-Enabled, NHC-Catalyzed Diastereoselective Aminoacylation of (Z/E)-β-Methylstyrenes with Benzoyl Saccharin.
Mingrui Li, Xiao Song, Jiuli Xia, Xueyun Lu, Jiaqiong Sun, Yan Li, Guangfan Zheng, Tao Xiong, Qian Zhang
Published: 202610.1021/acs.orglett.5c04959
Abstract
Stereoconvergent difunctionalization of Z/E-mixed alkenes presents a fundamental challenge in organic synthesis. We herein report a dual NHC/photoredox catalytic system that addresses this challenge through oxidation of internal alkenes to radical ca…
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