Organic letters
Electrochemical Cascade Reaction for C(sp3)-H Tetrazolation of Saturated Heterocycles: Access to Tetrazole-5-thiones.
Xiao Yu, Xian Liu, Shengkui Jin, Yongzheng Yin, Yiping Liu, Yafei Ji
Published: 202610.1021/acs.orglett.5c04909
Abstract
Tetrazole-5-thiones, known for their biological activities, are synthesized electrochemically through a cascade reaction using commercially available isothiocyanates, azidotrimethylsilane, and heterocycles. This method not only broadens the substrate…
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